New fibre-reinforced composite for cranio-maxillofacial (CMF) and for next generation dental implants (Code: 3381)
What we offer:
The use of reinforced composites made of particulate fillers or reinforcing fibres has been gaining popularity in dental and medical fields. Several fibre reinforced composites are already known. The state-of-the-art fibre reinforced composites yield high strength properties and by selecting the multiphase resin matrix for the composite, the handling characteristics of the composite can be considerably improved.
On the other hand, a lot of development has occurred with bioactive materials, namely bioactive ceramics and glass and sol-gel processed silica. These materials can be used to achieve attachment of e.g. bone to a biomaterial surface after the material has been put in contact with tissue. An additional advantage of bioactive glass is its antimicrobial effect on the microbes existing for instance in sinuses of a bone. The need and indications for development of new kinds of materials result from disadvantages of the use of allografts. Risks for transmittable diseases (HIV, Creutzfeld-Jacob´s disease, etc) are related to allografting. Metals are not bioactive or osteoconductive, and their use results in stress shielding phenomena and bone atrophy of the adjacent bone. Metal implants cause also severe problems in magnetic resonance imaging (MRI) when diagnosing diseases of patients. These main disadvantages are well documented in large clinical series.
Although the current trend in biomaterial research is in biodegradable polymers and composites, there is a constant need for biostabile materials to be used in repairs of large bone defects. Key issues in biostabile composite development are biomechanical properties (E-modulus, structural stiffness, load-bearing capacity), porosity and bioactivity of the material.
What are we looking for:
- TYPE OF PARTNER SOUGHT:
- SPECIFIC AREA OF ACTIVITY OF THE PARTNER:
Medical technology companies which are engaged in developing, manufacturing and marketing cranio-maxillo-facial, dental implants and composite implants for surgical purposes, such as for bone grafting and as scaffold for stem cell seeding..
- TASK TO BE PERFORMED:
Further testing and development of innovation.